Postpartum depression (PPD) is a common and complex disease, which affects approximately 15% of women during childbirth. Recent research from the PACT Consortium (Postpartum Depression:
Due to Post-Depression and Treatment) has demanded classification of several potential subtypes of this heterogeneous disease and emerging differences were found in the beginning, severity, anxiety and thinking of suicide.
This previous study suggested using PACT data that three different subtypes of PPD can be distinguished based on the type and severity of symptoms and that play time plays a major role in the development of symptoms (See the previous publication of this article: PPD Asymmetry).
In comparison to those who show symptoms after birth, before the PPD begins, the difference in symptoms is that the time of initiation in the treatment ideas can play an important role.
In order to expand subtype symptoms, a second study was conducted using PACT data from 663 women between 19 and 40 years of age in seven of PACT’s 19 international sites.
All data sets included the possibility of the onset of perinatal depression and the completion of post-natal Edinburgh (EPDS). ).
To study the symptoms of general anxiety and to calculate the fluctuations in biological factors such as perinatal hormone, researchers use the RDoC norms developed by the National Institute of Mental Health, the main ingredient for breaking the EPDS into three characteristic dimensions and General factors analyzed.
The results of each of the symptom symptoms – sad mood, anxiety and hyalidonia – were measured severely during every three months of pregnancy and during 3 postpartum periods (0-4 weeks, 4-8 weeks, and 8 weeks).
Five subtypes of perinatal depression were identified by separating patterns of symptoms in women, which vary in severity, onset and in the type of symptoms:
Subtype 1: Severe severe depression occurs during the first trimester of pregnancy or more than 8 weeks after birth.
Sixty eight percent (98%) of this sub-species women were classified into lightweight, severe or very serious EPDS (EPDS 20.2) and they were suffering from symptoms of depression and severe anxiety, but they do not have a relatively high rate of anonia I was glad).
In this category (99%) almost all women support the ideas that harm themselves. Many women reported the history of depression before pregnancy, although data on the condition of depression was not collected before pregnancy.
Depression moderate anxiety, serious anxiety, takes part in the pattern of similar beginnings of depression.
Women had to suffer from mild anxiety and depression symptoms (average score of EPDS 16.0), and most also supported self-harming ideas (76%). Many of these women also reported symptoms of depression before pregnancy.
Concerned Hydonia, such as subtype1, resulting in high to medium and serious EPDS (mean EPDS 19.2).
Symptoms are often seen within 8 weeks of birth, with a rare presence during pregnancy, there is a serious concern and serious risk of ammonia, but some thoughts about self-harm.
Pure Andonia showed a low EPDS score (14.9), but almost half of women supported suicide ideas (47%).
Some women had started immediately during the postpartum period (0-4 weeks), but otherwise, the start time was spread evenly throughout the post-postpartum period of all pregnancy and studies.
Analyst Depression showed the emergence of peri-natal symptoms which were resolved during the EPDS assessment. Symptoms usually appear during the third trimester of pregnancy, and this subtype was marked significantly less than other subtype compared to EPDS (average 4.1).
According to the time of evaluation during pregnancy or postpartum period (as shown in Figure 3), the prevalence of these subtypes is prominent during the postpartum period (1, 2 and 3) with the concern of the subtype.
Looking at this sample at all point-points, half women had severe subtypes of depression (32%) or moderate (19%). In 26%, a subtype of depression has been determined, 12% has an eagle anadonia, and 11% has a pure anadonia.
Many clinically significant results were noticed. During pregnancy, the second or third trimester of depression was associated with better results in post-natal EPDS estimation.
On the contrary, during the first eight weeks of postpartum period, the symptoms were associated with a high rate of severe depression (about 4 times more than those reported by the beginning of pregnancy).
Looking at the massive hormonal fluctuation during pregnancy in the postpartum period, these hormonal changes can be spoiled in postpartum period, therefore, this discovery may indicate significant biological difference in the subspecies.
The barriers observed by the researchers include cross-browser analysis of existing data, which provides less reliable information than potential longitudinal data collection and can lead to uncertainty.
Seven selected sites can have selection criteria, recruitment settings and variables collected.
In the current study, the population studied due to the high proportion of white, married and highly educated participants can not be normal.
In the PACT data set, very little information about mental health diagnosis and other factors before pregnancy has been utilized which can affect mood and anxiety.
Despite these limitations, the results make an important contribution to improving the care of pregnant and post-natal women.
In this study, our understanding of the many forms of postpartum depression has been expanded, which clinically utilizes a new approach to diagnose the presence and quality of depressive symptoms during many perinatal periods.
It creates hypotheses for future work and highlights the importance of stitching of sub-types of medicines and the severity of the symptoms of women present with diagnostically different phenotypes of parental depression.
With further investigation of these phenotypes, therapists will be able to provide faster, more efficient identification and treatment of post-postpartum depression.